Tesamorelin restores that upstream signal
However, if youre on prescribed medications check with your prescribing clinician before supplementing, this is because berberine is known to interact with some medications as it inhibits several liver enzymes that are involved in drug metabolism
Astaxanthin (Antioxidant) 4 mg Powerful Antioxidant Protection, Eye and Skin Health, Oxidative Stress Resilience and Recovery Astaxanthin 4 mg, Now Foods is a premium supplement delivering Zanthin astaxanthin , extracted from the microalgae Haematococcus pluvialis
PLoS ONE 16 , e0257880 (2021)
Nutrition Reviews, 62(6), S3S12
As such it protects highly vulnerable DNA from damage (consider PRP53 Code Liposome Spray), binding heavy metals, removing toxins and enhancing immune function, particularly viral infections